
Pancreaticoduodenectomy (Whipple procedure)
The reference operation for tumours of the head of the pancreas and the peri-ampullary region, the pinnacle of digestive surgery.
What is it?

When is it indicated?
When the work-up confirms that the tumour can be completely removed, the Whipple procedure offers the best treatment prospect, carried out by a team well versed in this surgery.
This small area where the bile and pancreatic ducts join the intestine can be the site of tumours, often revealed by jaundice and amenable to this operation.
Tumours located at the end of the bile duct, near the pancreas, are treated by the same operation, which removes the entire affected region in a single block.
As the duodenum is intimately connected to the head of the pancreas, its tumours require this same en-bloc removal to be treated under good conditions.
Removing an at-risk lesion before it transforms makes it possible to act preventively, at the most favourable moment for the patient.
Preparation
Procedure
General anaesthesia with advanced monitoring
Abdominal exploration confirming the feasibility of the removal
En-bloc removal of the head of the pancreas, the duodenum and the lower bile duct
Triple digestive reconstruction (pancreatic, biliary and gastric)
Placement of monitoring drains
Transfer to intensive care for close monitoring
Duration
5 to 7 hours
Aftercare & Recovery
Recovery takes place first in intensive care and then on the ward, with a very gradual return to eating over several days. Full convalescence takes several weeks, accompanied by close nutritional and medical follow-up. The quality of life regained after recovery is generally good.
Risks and side effects
These risks remain rare. Your surgeon will inform you in detail before the procedure.
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